Toddlers Learn from Pictures!

I’m attending yet another conference, so my posts might get a little shorter and more sparse this week, but… It’s also a visualization conference, so perhaps I’ll be inspired!

A Reuters article today cites newly-published research showing that infants and toddlers learn from pictures! To quote, “Illustrations in picture books go beyond entertaining children and teach them how to navigate the world, according to a study published by the American Psychological Association on Sunday.”

Evidently, the way young’ns interact with images has not been well studied up to this point, so the research brings an added level of rigor to the discussion of using visuals for early-age instruction.

A tantalizing line in the article states that “The results varied according to the children’s ages and whether a photograph or drawing was used,…” Leaving me crying out for more. Varied how? Photos versus drawings? Which was better? How do kids interpret drawings versus photos in terms of depicting reality? So many questions! I couldn’t track down the article, however, so the questions remain unanswered for now.

The research was done in part by Judy DeLoache at the University of Virginia Child Study Center.

Imaging hA3G

I am under the impression that the image above shows the first-ever “snapshot” of the structure of an enzyme that could help resist HIV and the onset of AIDS.

According to an article from Reuters, some small percentage of people possess hA3G in spades, and they can fight off the effects of HIV for longer than others. The question is how. Knowing what the enzyme looks like helps scientists understand the chemical processes better and could help “design a drug to mimic its effects and perhaps provide the first medicine to boost the ability to fight AIDS,” as the Reuters reportage puts it.

According to the associated research article, “high-molecular-mass (HMM) complex […] can be transformed in vitro into an active, low-molecular-mass (LMM) variant comparable to that of HIV-non-permissive CD4+ T-cells.” Which seems to be something good.

The point, as far as this blog is concerned, is that the general structure of this important compound has been unlocked—or at least the first steps have been taken to understanding more about its elusive nature. Moreover, the spatial depiction of the chemical structure is fundamental to unlocking its secrets. And that’s what visualization is all about.

Bloody Palpitations

The above image comes from a press release from MIT (which can be read ina recent issue of MIT’s Tech Talk as well) that describes work being done on imaging living cells. The cells in question (as the colors chosen for the height scale so transparently suggest) are red blood cells, and the “quantitative phase imaging” technique allows for observations of the cells’ shapes down to a few nanometers.

The spiffy thing? High resolution in scale allows us to see fluctuations in the membranes as they allow ions into and out of the cell. Cells prone to swelling can burst, and swollen cells also palpitate less, so studying their motion numerically is a boon to understanding the physical processes at work. This could help us understand diseases such as malaria and sickle-cell anemia at the scale of the blood cells themselves.

(As far as I understand, quantitative phase imaging has been used in Transmission Electron Microscopy (TEM) for some time, so its application in light spectroscopy is a new thing. Especially since you can’t use TEM to observe living cells. Just FYI, this differs from the technique I’d described earlier on this blog for tagging individual stem cells in bone marrow.)

I quite like the image above. What’s the Hitchcock quote? “Blood is jolly, red.” You take one look and you get a general sense of what’s going on, and the scale to the right provides a little more info. Nice.

Numerous other pictures accompany the press release, including a series of false-color images that reveal both normal and abnormal cells. Sadly, the captions shed little light (spectroscopic or otherwise) on what the images actually depict. Particularly egregious is a rather incomprehensible figure—according to its caption, it “shows the correlation between cell shape and membrane dynamics,” but what exactly does that mean? Of all places, it seems that MIT would want to present imagery that could be read across a variety of technical disciplines, and this figure doesn’t cut it! Couldn’t we get more information than “Δu&sup2(q)” versus “q” (although they kindly include units)? I’ll tell you this much—a little research revealed that “discocyte,” “echinocyte,” and “spherocyte” refer to diffferent red blood cell morphologies (cf. a “scientific highlight” from Australia for more information).

My gripe here is just that captions, particularly in press releases, should give enough information for a well-informed non-specialist to get a handle on the information being presented. After all, science reporters are most likely generalists who will appreciate whatever cues you can provide.

(Thanks to Phile Schewe and his “Physics News Update.” Also, I ran across another informative web site in my searches. Lots of info about cell biology. And very difficult quizzes!)

Airport Images

Having returned to New York from my trip, I figured I could offer two airport observations…

While waiting for my flight at the Lousiville International Airport, I had a good view of a pari of video panels set up by the Standiford Art Foundation as part of their “Video Art Project.” The three pieces each had their merits, but I found myself mildly intrigued by Thomas C. deLisle’s “Transition” (2005), which consisted entirely of Earth imagery from orbit.

I should first note that the screens were situated slightly off the beaten path (albeit on the way to restrooms, which is often a good thing), so no more than fifty or sixty people passed by in the hour or so I sat nearby. Of those, only five or six stopped to look, and highly subjectively, I’d say that the terrestrial imagery held their attention longer than the other pieces—one a somewhat abstract view of reflections on water, the other a continuous drive-by of suburbia. But people didn’t linger very long, usually only fifteen or twenty seconds and only once more than a minute.

The problem I had with the piece was the rapidity with which images cut from one to the next, leaving little time to absorb anything within the frame. Plus, the physical set-up consisted of two screens with separate content on both, making the transitions feel even faster-paced. I kept looking for some connection between sequential frames or paired images, but none struck me. Between the speed of cuts and the randomness of the images, the net effect was a bit like watching a screen saver with poor settings. But the Earth stuff seemed to have a slight allure for passers-by… Perhaps if it had offered more time to absorb the visuals?

On a related airport topic, I also took a look at Accenture’s interactive video wall at O’Hare International Airport. This has nothing to do with science, per se, but in fact, it would be nice if it did! When you step up to the screen, you’re given options for “Weather,” “News,” “Sports,” “Entertainment,” and “Tiger Woods.” Why not “Science”? Given the degree to which science and technology affects our lives, it seems like a no-brainer. Then we could implore Accenture for data on how often people select the “Science” option relative to others.

I’ve read some rather critical appraisals of the technology, but in fact, people spent a bit of time interacting with the thing (more than looked at the video art in Louisville, that’s for sure), and its interface felt completely transparent to basically everybody who stepped up to the screen. That strikes me as successful. I mean, the Windows-like grassy field and blue sky kinda creeps me out, but even I won’t hold that against ’em. Too much.

Roving Mars

So I finally saw Roving Mars, the Imax® film about the MER mission—those wee rovers on Mars that have currently enjoyed more than 1,000 sols (i.e., Martian days, which clock in about three percent longer than terrestrial days) of exploration on the Red Planet.

First off, the film tells its story brilliantly. From the human scientists to the anthropomorphized rovers, the characters play roles that win over the audience and keep the narrative moving. Furthermore, the movie manages to balance the engineering and the science, which has proven tricky in other documentaries I’ve seen, particularly when they came out early in the mission.

But what I find intriguing about the film is something that my coworker Carter Emmart mentioned right after he saw it—the incredibly blurred line between real and computer-generated imagery. Actual rover images segue seamlessly into animated shots, and it sometimes takes a moment (for an expert, if I may refer to myself thusly) to distinguish between the two. I even got into a discussion with a planetary geologist afterward about whether one of the scenes was computer-generated or shot on Earth!

This is more than a testament to software tools and technological acumen. It also raises questions about how audiences perceive science content. If we don’t let people know the source of the imagery we present, do they end up thinking more or less of the end product? I’d be curious to know when (or if) they perceive the shift from reality to animation. One would hope that people would recognize that no film crew followed the rocket into space and no aerial cameras exist to execute the fly-overs of the rovers on Mars, but… And conversely, do people realize how much even the computer-generated media is informed by the science? Does it matter?

In surveys conducted for the Cosmic Collisions show production at my home institution, we found that people placed great value on knowing that visuals were rooted in scientific visualization of real computational data—and they put even higher stock in imagery that came from spacecraft observations. Thus, an actual image of the Sun had greater cachet than a computer simulation, which in turn meant more to people than an artist’s rendition.

So is it important to make sure people know what they’re looking at? You certainly don’t want to disrupt the flow of the story, but Roving Mars chose, as most pieces do, not to address the issues at all. That makes me a little uncomfortable.

At the end of the day (or the sol), the film weaves an exciting, even touching narrative, and the detailed, highly accurate imagery serves the subject well. I certainly think that the richness of the data—of realism—infuses every frame of the film with greater impact than “mere artistry” could accomplish. When you look at the real stuff, you get a subliminal sense of the complexity that I think most people find satisfying.

Snake on a (Galactic) Plane

Still at my conference, I’m going to take the easy way out on today’s image. A nifty picture, indeed, although I’m inordinately fond of infrared images, and Spitzer (back when it was still SIRTF) paid for my summer employment back in college, so I might ba a tad biased.

I’m inordinately fond of puns as well, but… Yeesh! That title. On the phone just now, I confirmed that I know the person responsible for it, too. It’s a small astro-viz community out there.

Fading Echo

Attending a conference in Northern Indiana has proven a little distracting, particularly since I’ve decided to prepare my talk using the LaTeX Beamer class instead of PowerPoint. It produces some handsome PDFs, but climbing the learning curve is a tad painful…

At any rate, that explains my fall back to astronomy. Haste. So it’s just another lovely image today, released as part of a Hubble Space Telescope announcement from ESA. If you have a chance, take a look at even the moderately higher-resolution image available online. The loops and whorls visible in the image above (or at least its higer-resolution counterpart) appear much more distinct than similar features in earlier images of the object.

You see, V838 Monocerotis isn’t like most nebulae—Orion and the Eagle, for example, glow because the gas inside them is heated up and ionized—instead, V838 glows by reflected light. Dust around the central star has been illuminated by an event that took place several years ago, a little like a flash going off in a darkened room, except that it takes years for light to traverse the extent of the surrounding material (thus, to continue the darkened room analogy, you’d need to think of the far wall of the room illuminated long after chairs, tables, or whatever in the foreground would be revealed by the flash). An earlier Hubble announcement about the object reveals V838 growing over time, not because the cloud itself is expanding, but because it has been lit by a burst of light that continues to wash over the dust that enshrouds the central source.

The nickname for this is a “light echo,” suggesting the bouncing of sound off increasingly distant hilltops. Sadly, like an echo, V838 will continue to grow dimmer over time (the intensity of light, after all, falls off as the square of the distance), so we should enjoy the fabulous images while we can.

Periodic Spiral

The image above shows a version of the periodic table of the elements, visualized by Jeff Moran. I ripped the image from a PDF offered up on his website, which also links to a piece of software that uses the above image as a basis for exploring the periodic table—lots of information is given on each element, although you have to shell out $50.00 to get the fully functional version.

Moran’s software ain’t new, but for some reason, the New York Times chose to highlight it in today’s Science Times, along with other ways of arranging the elements to highlight relationships that the typical rectangular arrangement misses. (The article also references Edgar Longman’s “Chemical Galaxy” image, for which I have great fondness.)

What I love about these re-imaginings of the familiar (well, familiar to some) is that they make one look at things differently. I can’t claim to have mcuh of an intuitive sense of the structure of the periodic table, but what I understand, I see more clearly in these newer versions. And I feel compelled to note that what I do understand of the periodic table, I gleaned from P.W. Atkins’s brilliant Periodic Kingdom, which describes the familiar, rectangular table as a landscape of different attributes—binding energies, specific heats, and other such measurable quantities.

So… Take the Times’s lead and take aother look at the periodic table!

Stem Cell, Stem Cell, Burning Bright

Researchers at the University of Michigan Medical School and Japan’s University of Tsukuba have announced the ability to tag hematopoietic stem cells (HSCs) in living bone marrow—which means they managed to make the gene for green fluorescent protein (GFP) express itself only in HSCs and not in the surrounding cells. The glowing green blob in the image above represents a stem cell, all on its lonesome, in the midst of mouse bone (as opposed to mouse brains).

HSCs are the little folks responsible for forming blood cells and supporting the immune system, and they don’t survive too long outside of bone marrow, so it’s important to track their behavior where they’re most at home. The press release also links to a time-lapse QuickTime of the luminescent stem cell, although I should warn you that not much happens. The important thing to note is that the stem cell seems rather lonely; instead of hanging out with a bunch of pals, it (like the cheese) stands alone.

The technique of tagging cells with the gene for bioluminescence hasn’t been around too terribly long, but it provides a remarkably straightforward way of visualizing what’s happening at the cellular (or even sub-cellular) level. The image above gets the message across quite clearly.

Coincidentally, I recently picked up an impressive (and well-illustrated) tome that describes the development of bioluminescent tagging for use in research. Aglow in the Dark: The Revolutionary Science of Biofluorescence is written by two insiders in the field, who give an intimate introduction to the history of the topic, while providing truly enlightening (sorry) background to the scientific and technical challenges. Quite a fascinating little book.

Pulsed Oddity

Asleep at the virtual wheel, I somehow missed this week’s announcement of winners for the Second NRAO/AUI Radio Astronomy Image Contest. The above image represents one of the more puzzling choices for inclusion among the honorees.

I mean, Iike the idea of a conceptual graphic rather than the typical “pretty picture”: the image above tells a story, admirably but perhaps unclearly. Being only marginally acquainted with Shapiro delays, I correctly guessed that the abscissa represents time (the cartoon above the data plot helped), but what’s up with the ordinate? It’s a pulsar, so I’m guessing timing, but would it hurt to tell us?

Plus, the cartoon in the middle gets a little confusing. The ellipses suggest that we’re seeing the system from an oblique angle, but the third image from the left makes the beam of light (which feels as though it’s coming out of the plane of the image) appear to be in the plane of the orbits. That really threw me off.

Anyway, eight winners appear to have been selected from 13 entries. Not bad odds. I might have to enter next year…

And now I’m running late for a dinner. So I’ll sign off for now.